Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 19/20 | 0.45 |
| ▸ | GABRD | O14764 | 19/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 19/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 19/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 19/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 19/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 19/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 19/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 19/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 19/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 19/20 | 0.45 |
| ▸ | GABRE | P78334 | 19/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 19/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 19/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 19/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 19/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2836868 | 0.92 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7027964 | 0.91 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7670542 | 0.89 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055896 | 0.88 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6055689 | 0.87 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2833453 | 0.86 | GABRP (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7023345 | 0.86 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7234108 | 0.85 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7656516 | 0.85 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL14567180 | 0.85 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105969-A1 | Anthelmintic compositions | BRUCE CHRISTOPHER I | 2006-05-18 | — | — | US | claimed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | claimed |
| EP-3324955-B1 | COMPOSITION COMPRISING FIPRONIL AND DINOTEFURAN FOR USE IN AMETHOD OF CONTROLLING FLEAS IN NON HUMAN MAMMALS | CEVA SANTE ANIMALE (FR) | 2026-04-29 | — | — | EP | disclosed |
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | Ceva Santé Animale (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2020-05-28 | — | — | US | disclosed |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2018-08-02 | — | — | US | disclosed |
| EP-3324955-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS | Ceva Sante Animale (FR) | 2018-05-30 | — | — | EP | disclosed |
| EP-3259990-A1 | METHODS FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-12-27 | — | — | EP | disclosed |
| WO-2017017021-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS | CEVA SANTE ANIMALE (FR) | 2017-02-02 | — | — | WO | disclosed |
| EP-3120846-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-01-25 | — | — | EP | disclosed |
| US-9339033-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | MERIAL, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| EP-0967206-A1 | Derivatives of N-phenylpyrazoles | RHONE POULENC AGRICULTURE LTD. (GB) | 1999-12-29 | — | — | EP | disclosed |
| US-5916618-A | PESTICIDE FOR MEDICATED FEEDSTUFF, DIETARY CONCENTRATE OR SUPPLEMENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-06-29 | — | — | US | disclosed |
| US-5714191-A | PESTICIDES USED IN MEDICATED FEEDSTUFF, MINERAL SALT LICK OR EDIBLE BAIT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-02-03 | — | — | US | disclosed |
| US-5608077-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-03-04 | — | — | US | disclosed |
| US-5547974-A | INSECTICIDES, NEMATOCIDES, ANTHELMINTICS | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-08-20 | — | — | US | disclosed |
| EP-0418016-B1 | N-phenylpyrazole derivatives as insecticides | RHONE POULENC AGRICULTURE (GB) | 1995-05-03 | — | — | EP | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| EP-0418016-A1 | N-phenylpyrazole derivatives as insecticides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
| EP-0295117-A1 | Derivatives of N-phenylpyrazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | NISCH, NAMPT, TYR | GABRP 2904/4885GABRD 3255/4885GABRA1 3400/4885 |
| US-20060105969-A1 | Anthelmintic compositions | TUBB, TUBA3C, CYP51A1 | GABRP 2567/4885GABRD 2908/4885GABRA1 3528/4885 |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | GABRP 2904/4885GABRD 3255/4885GABRA1 3400/4885 |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | GABRP 2904/4885GABRD 3255/4885GABRA1 3400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.