Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.77 |
| ▸ | CDK9 | P50750 | 1/20 | 0.77 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.77 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | ACP1 | P24666 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA9 | Q16790 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylurea SCHEMBL133103 | 0.88 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL11884167 | 0.86 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL12011007 | 0.86 | CA12 (0.69) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL29392345 | 0.85 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL30786615 | 0.85 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL28431956 | 0.85 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL3037927 | 0.85 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11059378 | 0.85 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL4421237 | 0.85 | ACP1 (0.69) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Acetanilide SCHEMBL397904 | 0.83 | NAPRT (0.79) | SMN1; SMN2EPHX1TSHRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116380-A | Low-cost method for synthesizing 2, 6-dichloroaniline | 浙江解氏新材料股份有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-111116380-A | Low-cost method for synthesizing 2, 6-dichloroaniline | 浙江解氏新材料股份有限公司 | 2020-05-08 | — | — | CN | disclosed |
| CN-111116380-A | Low-cost method for synthesizing 2, 6-dichloroaniline | 浙江解氏新材料股份有限公司 | 2020-05-08 | — | — | CN | disclosed |