Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | RAB9A | P51151 | 10/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888411 | 0.89 | RAB9A (0.67) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL28390817 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL28393073 | 0.83 | ALDH1A1 (0.72) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL28526056 | 0.81 | HPGD (0.63) | SMN1; SMN2ALDH1A1TP53MAPTKDM4E | |
| SCHEMBL28526054 | 0.81 | HPGD (0.63) | SMN1; SMN2ALDH1A1TP53MAPTKDM4E | |
| SCHEMBL28390821 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL3585075 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL28393627 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL28476359 | 0.72 | NPC1 (0.78) | SMN1; SMN2ALDH1A1TP53NPC1RAB9A | |
| SCHEMBL17216060 | 0.72 | MEN1 (0.58) | ALDH1A1RAB9AMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138377-B | Vanilamide derivative and preparation method and application thereof | 长沙理工大学 | 2023-03-28 | — | — | CN | claimed |
| CN-111138377-A | Vanilamide derivative and preparation method and application thereof | 长沙理工大学 | 2020-05-12 | — | — | CN | claimed |
| CN-111138377-B | Vanilamide derivative and preparation method and application thereof | 长沙理工大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-111138377-A | Vanilamide derivative and preparation method and application thereof | 长沙理工大学 | 2020-05-12 | — | — | CN | disclosed |