Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 12/20 | 0.47 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.46 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28011530 | 0.88 | MAPK1 (0.64) | MAPK1GPR132CMKLR2CMKLR1HTR1A | |
| SCHEMBL28397433 | 0.84 | NOS3 (0.51) | MAPK1GPR132MAOB | |
| SCHEMBL28397085 | 0.82 | MAPK1 (0.42) | MAPK1HTR1ADRD2CYP11B1 | |
| SCHEMBL28396007 | 0.82 | MAOB (0.62) | MAOB | |
| SCHEMBL791886 | 0.81 | MAOB (0.66) | MAPK1GPR132HTR1ADRD2MAOB | |
| SCHEMBL4808799 | 0.80 | CHRNB2 (0.51) | MAOB | |
| SCHEMBL22964344 | 0.79 | MAPK1 (0.58) | MAPK1GPR132CMKLR2CMKLR1 | |
| SCHEMBL21477258 | 0.78 | MAPK1 (0.57) | MAPK1GPR132CMKLR2CMKLR1HTR1A | |
| SCHEMBL3998456 | 0.78 | MAOB (0.66) | MAPK1GPR132CMKLR2CMKLR1CYP11B1 | |
| SCHEMBL13452125 | 0.78 | MAPK1 (0.57) | MAPK1GPR132HTR1ADRD2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-B | BTK inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |