SCHEMBL28393201

SCHEMBL28393201

CCC[SiH](CCN1CCNCC1)OC

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CXCR4 P61073 2/20 0.36
GNAO1 P09471 4/20 0.33
GNAI3 P08754 3/20 0.33
GNAI1 P63096 3/20 0.33
HSD17B10 Q99714 1/20 0.33
SOD3 P08294 2/20 0.33
HRH2 P25021 1/20 0.33
HRH1 P35367 1/20 0.33
SIGMAR1 Q99720 3/20 0.33
SLC6A4 P31645 1/20 0.32
RAD52 P43351 1/20 0.32
PIM1 P11309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29030826 0.79 POLB (0.41) POLBSMN1; SMN2MEN1KMT2ACXCR4
SCHEMBL28394880 0.77 POLB (0.39) POLBSMN1; SMN2MEN1KMT2ACXCR4
Piperazine SCHEMBL28393204 0.74
SCHEMBL4069049 0.73 POLB (0.36) POLBSMN1; SMN2MEN1KMT2ACXCR4
SCHEMBL6927442 0.73
SCHEMBL178388 0.73
SCHEMBL340594 0.72
SCHEMBL774158 0.72 SMN1; SMN2 (0.38) POLBSMN1; SMN2MEN1KMT2ACXCR4
SCHEMBL3810144 0.72 CXCR4 (0.46) POLBSMN1; SMN2MEN1KMT2ACXCR4
SCHEMBL28394895 0.71 POLB (0.41) POLBSMN1; SMN2MEN1KMT2ACXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111117225-A Flame-retardant bio-based polyamide material and preparation method thereof 广东泰塑新材料科技有限公司 2020-05-08 CN disclosed