SCHEMBL774158

SCHEMBL774158

CCO[SiH](CCN1CCNCC1)OCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
CXCR4 P61073 2/20 0.37
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
SIGMAR1 Q99720 4/20 0.33
ALDH1A1 P00352 1/20 0.33
RAD52 P43351 1/20 0.33
GNAI3 P08754 3/20 0.31
GNAO1 P09471 3/20 0.31
GNAI1 P63096 3/20 0.31
HRH2 P25021 1/20 0.31
HRH1 P35367 1/20 0.31
LTA4H P09960 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4065756 0.89 CXCR4 (0.43) SMN1; SMN2POLBCXCR4SIGMAR1GNAI3
SCHEMBL2403147 0.87 CXCR4 (0.44) SMN1; SMN2POLBCXCR4SIGMAR1ALDH1A1
SCHEMBL4069049 0.85 POLB (0.36) SMN1; SMN2POLBCXCR4HSD17B10MEN1
SCHEMBL537898 0.80 SMN1; SMN2 (0.36) SMN1; SMN2POLBCXCR4SIGMAR1
SCHEMBL29030826 0.80 POLB (0.41) SMN1; SMN2POLBCXCR4HSD17B10MEN1
SCHEMBL2762716 0.77 ALDH1A1 (0.40) SMN1; SMN2MEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL4063053 0.75 CXCR4 (0.41) SMN1; SMN2POLBCXCR4MEN1KMT2A
SCHEMBL4067827 0.74
SCHEMBL4065762 0.74 CXCR4 (0.42) SMN1; SMN2POLBCXCR4SIGMAR1ALDH1A1
SCHEMBL4068404 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US claimed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US disclosed
EP-3877438-B1 METHOD FOR THE PREPARATION OF SILANE-MODIFIED POLYMERS MERZ BENTELI AG (CH) 2023-06-14 EP disclosed
US-20210395450-A1 METHOD FOR PRODUCING SILANE-MODIFIED POLYMERS MERZ+BENTELI AG (CH) 2021-12-23 US disclosed
EP-3877438-A1 METHOD FOR PRODUCING SILANE-MODIFIED POLYMERS merz+benteli ag (CH) 2021-09-15 EP disclosed
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US disclosed
US-20160108271-A1 SILVER NANOPARTICLE INKS COMPRISING AMINOMETHYLSILANES XEROX CORPORATION 2016-04-21 US disclosed
US-8361176-B2 Hydrophilic and hydrophobic silane surface modification of abrasive grains SAINT-GOBAIN ABRASIVES, INC. (US) 2013-01-29 US disclosed
US-20120066980-A1 Hydrophilic and Hydrophobic Silane Surface Modification of Abrasive Grains SAINT-GOBAIN ABRASIFS (FR) 2012-03-22 US disclosed
US-8080500-B2 Amine tungstates and lubricant compositions KING INDUSTRIES, INC. (US) 2011-12-20 US disclosed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US disclosed
US-20090029888-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. 2009-01-29 US disclosed
US-20080194440-A1 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS RAVICHANDRAN RAMANATHAN 2008-08-14 US disclosed
EP-1714968-B1 Protected piperazino group-bearing organoxysilane compound and making method SHINETSU CHEMICAL CO (JP) 2008-07-16 EP disclosed
EP-1907517-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS King Industries, Inc. (US) 2008-04-09 EP disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM SMN1; SMN2 1719/4885POLB 1859/4885CXCR4 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.