Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174907 | 0.85 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL168484 | 0.85 | GAA (0.37) | DGAT1LMNAKMT2A | |
| SCHEMBL28562263 | 0.83 | NPC1 (0.33) | DGAT1LMNAKMT2A | |
| SCHEMBL23910452 | 0.83 | POLB (0.39) | DGAT1LMNA | |
| SCHEMBL23910411 | 0.82 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL23910369 | 0.81 | P2RY14 (0.35) | DGAT1 | |
| SCHEMBL21222348 | 0.80 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL23910436 | 0.79 | ALDH1A1 (0.36) | DGAT1KMT2A | |
| SCHEMBL24852733 | 0.78 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL26675183 | 0.77 | GAA (0.40) | DGAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166142-B | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 上海轶诺药业有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-113166142-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 上海轶诺药业有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-111171019-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 上海轶诺药业有限公司 | 2020-05-19 | — | — | CN | disclosed |