SCHEMBL8397115

SCHEMBL8397115

CCOC(OCC)(OCCn1cnc2c(N)ncnc21)P(=O)(O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 3/20 0.61
SLC22A6 Q4U2R8 2/20 0.61
ADORA2A P29274 5/20 0.54
ADORA1 P30542 3/20 0.54
ADORA2B P29275 1/20 0.54
ABCB11 O95342 1/20 0.52
POLA1 P09884 1/20 0.52
POLG P54098 1/20 0.52
FAP Q12884 1/20 0.52
NSD3 Q9BZ95 3/20 0.51
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
PI4KA P42356 1/20 0.50
PI4K2B Q8TCG2 1/20 0.50
PI4K2A Q9BTU6 1/20 0.50
PI4KB Q9UBF8 1/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.49
NSD2 O96028 2/20 0.48
ENPP1 P22413 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3302562 0.86 FGFR1 (0.64) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL8400653 0.86 CDK1 (0.51) FGFR1SLC22A6ABCB11POLA1POLG
SCHEMBL28394183 0.83 CYP3A4 (0.65) ADORA2AADORA1FAPCYP3A4
SCHEMBL8400867 0.81 HSP90AB1 (0.45)
SCHEMBL7756283 0.80 SLC22A6 (0.61) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL7757185 0.80 FGFR1 (0.58) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL3303774 0.78 SLC22A6 (0.59) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL1933784 0.78 SLC22A6 (0.65) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL28797058 0.77 SLC22A6 (0.67) FGFR1SLC22A6ADORA2AADORA1ADORA2B
SCHEMBL30536876 0.77 FGFR1 (0.82) FGFR1SLC22A6ADORA2AADORA1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115275019-A Perovskite solar cell and preparation method thereof 宣城先进光伏技术有限公司 2022-11-01 CN claimed
CN-115275019-A Perovskite solar cell and preparation method thereof 宣城先进光伏技术有限公司 2022-11-01 CN disclosed
US-5874577-A Method for the preparing 9-12-(Diethoxyphosphonomethoxy)ethyl!adenine and analogues thereof MEDICHEM RESEARCH, INC. (US) 1999-02-23 US disclosed