Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.52 |
| ▸ | HSD11B2 | P80365 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | CPB1 | P15086 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2825063 | 0.95 | HSD11B1 (0.56) | HSD11B1HSD11B2ALDH1A1GAATSHR | |
| SCHEMBL1846642 | 0.95 | HSD11B1 (0.56) | HSD11B1HSD11B2ALDH1A1GAATSHR | |
| SCHEMBL1845687 | 0.95 | HSD11B1 (0.56) | HSD11B1HSD11B2ALDH1A1GAATSHR | |
| SCHEMBL1846641 | 0.95 | HSD11B1 (0.56) | HSD11B1HSD11B2ALDH1A1GAATSHR | |
| SCHEMBL12578487 | 0.95 | HSD11B1 (0.56) | HSD11B1HSD11B2ALDH1A1GAATSHR | |
| SCHEMBL1844036 | 0.86 | HSD11B1 (0.57) | HSD11B1HSD11B2TSHREPHX2CPB1 | |
| SCHEMBL1844035 | 0.86 | HSD11B1 (0.57) | HSD11B1HSD11B2TSHREPHX2CPB1 | |
| SCHEMBL1044166 | 0.86 | HSD11B1 (0.57) | HSD11B1HSD11B2TSHREPHX2CPB1 | |
| SCHEMBL1844038 | 0.86 | HSD11B1 (0.57) | HSD11B1HSD11B2TSHREPHX2CPB1 | |
| SCHEMBL2837021 | 0.85 | CPB1 (0.49) | HSD11B1HSD11B2ALDH1A1GAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123838-A2 | NOVEL AMIDE AND AMIDINE DERIVATIVES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2010-10-28 | — | — | WO | disclosed |