SCHEMBL28396374

SCHEMBL28396374

Cc1ccc2oc3c(ccc4ccccc43)c(=O)c2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 9/20 0.48
MAPT P10636 7/20 0.48
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
HPGD P15428 7/20 0.46
ALDH1A1 P00352 7/20 0.46
ABCG2 Q9UNQ0 4/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HTT P42858 3/20 0.46
ABCC1 P33527 3/20 0.46
MEN1 O00255 1/20 0.46
HSD17B10 Q99714 4/20 0.44
TP53 P04637 2/20 0.44
CYP3A4 P08684 2/20 0.44
ABCB1 P08183 2/20 0.44
ALOX15 P16050 1/20 0.44
PDE5A O76074 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28402137 0.90 KMT2A (0.55) KMT2AKDM4EMAPTMAOAMAOB
SCHEMBL10109872 0.88 KMT2A (0.51) KMT2AKDM4EMAPTMAOAMAOB
SCHEMBL12764548 0.82 MAOA (0.61) KMT2AKDM4EMAPTMAOAHPGD
SCHEMBL28889872 0.82 CYP1A1 (0.53) KMT2AKDM4EMAPTHPGDALDH1A1
SCHEMBL31080981 0.82 KMT2A (0.47) KMT2AKDM4EMAPTMAOAHPGD
SCHEMBL22326344 0.82 KMT2A (0.47) KMT2AKDM4EMAPTMAOAHPGD
SCHEMBL20350074 0.82 KDM4E (0.50) KMT2AKDM4EMAPTMAOAMAOB
SCHEMBL28400048 0.82 MAOA (0.68) KMT2AKDM4EMAPTMAOAHPGD
SCHEMBL23060759 0.80 KMT2A (0.45) KMT2AKDM4EMAPTMAOAMAOB
SCHEMBL10109866 0.80 KMT2A (0.53) KMT2AKDM4EMAPTMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057037-B Ultraviolet light-promoted synthesis method of xanthone compound 浙江工业大学 2021-07-23 CN disclosed
CN-111057037-A Ultraviolet light-promoted synthesis method of xanthone compound 浙江工业大学 2020-04-24 CN disclosed