SCHEMBL22326344

SCHEMBL22326344

O=c1c2cc(Br)ccc2oc2c1ccc1ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
ABCG2 Q9UNQ0 3/20 0.46
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 3/20 0.44
HSD17B10 Q99714 2/20 0.44
HTT P42858 2/20 0.44
ABCC1 P33527 2/20 0.44
CYP1A1 P04798 2/20 0.44
CYP1B1 Q16678 2/20 0.44
ALOX15 P16050 1/20 0.44
PDE5A O76074 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
ABCB1 P08183 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP19A1 P11511 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31080981 1.00 KMT2A (0.47) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL22337130 0.90 KMT2A (0.48) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL28401337 0.90 PTGS2 (0.51) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL29595968 0.88 KDM4E (0.44) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL16067537 0.88 KDM4E (0.44) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL19513684 0.83 ESR2 (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL12764548 0.82 MAOA (0.61) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL28396374 0.82 KMT2A (0.54) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL28889872 0.82 CYP1A1 (0.53) KMT2AABCG2KDM4EALDH1A1HPGD
SCHEMBL29902443 0.80 GABRP (0.47) KMT2AKDM4EALDH1A1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113227076-A Novel heterocyclic compound and organic light emitting device using the same 株式会社LG化学 2021-08-06 CN disclosed
WO-2020162703-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-08-13 WO disclosed
WO-2020162703-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-08-13 WO disclosed