SCHEMBL808105

SCHEMBL808105

O=S(=O)(Nc1ccc(O)cc1)c1ccc2ccccc2c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.72
ALDH1A1 P00352 3/20 0.69
LMNA P02545 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
GAA P10253 1/20 0.69
PGR P06401 1/20 0.68
KMT2A Q03164 5/20 0.64
MEN1 O00255 4/20 0.64
PKM P14618 1/20 0.64
PKLR P30613 1/20 0.64
STAT3 P40763 1/20 0.64
UQCRB P14927 1/20 0.62
HDAC1 Q13547 2/20 0.61
PLAU P00749 2/20 0.61
KAT6A Q92794 1/20 0.61
AKR1C3 P42330 1/20 0.59
MAPT P10636 1/20 0.59
HDAC3 O15379 1/20 0.59
HDAC4 P56524 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556438 0.87 KMT2A (0.60) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL29549847 0.86 PGR (0.77) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL20021987 0.86 PGR (0.77) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL28396503 0.86 PGR (0.77) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL3258120 0.84 KMT2A (0.68) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9942088 0.84 ATM (0.72) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL9479593 0.84 PGR (0.73) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL20021984 0.84 ATM (0.72) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL7782154 0.83 ALDH1A1 (0.77) ATMALDH1A1LMNASMN1; SMN2GAA
SCHEMBL8275407 0.82 ALDH1A1 (1.00) ATMALDH1A1LMNASMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617415-B1 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) 2016-04-20 EP claimed
US-9834022-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2017-12-05 US disclosed
EP-3031611-B1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD (JP) 2017-09-27 EP disclosed
US-20160332469-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2016-11-17 US disclosed
EP-3031611-A1 THERMAL RECORDING MATERIAL Mitsubishi Paper Mills Limited (JP) 2016-06-15 EP disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells MSP CO., LTD. (KR) 2015-09-10 US disclosed
US-9068166-B2 Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2015-06-30 US disclosed
US-9068166-B2 Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2015-06-30 US disclosed
EP-2096149-B1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED MITSUBISHI PAPER MILLS LTD (JP) 2014-10-22 EP disclosed
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-12 US disclosed
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2013-09-12 US disclosed
US-8288313-B2 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-16 US disclosed
US-8283285-B2 Scratch color-developable ink and invisible information printed sheet MITSUBISHI PAPER MILLS LIMITED (JP) 2012-10-09 US disclosed
WO-2012036512-A2 USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS 연세대학교 산학협력단 (KR) 2012-03-22 WO disclosed
US-20100069240-A1 THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LIMITED (JP) 2010-03-18 US disclosed
US-20100021702-A1 SCRATCH COLOR-DEVELOPABLE INK AND INVISIBLE INFORMATION PRINTED SHEET MITSUBISHI PAPER INK MFG. CO., LTD. (JP) 2010-01-28 US disclosed
EP-2096149-A1 INK FOR SCRATCH COLORING AND SHEET WITH INVISIBLE INFORMATION PRINTED Mitsubishi Paper Mills Limited (JP) 2009-09-02 EP disclosed
US-20070026259-A1 Thermal recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2007-02-01 US disclosed
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130236969-A1 Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes COL2A1, MYADM, COL1A1 ATM 2538/4885ALDH1A1 47/4885LMNA 2008/4885
US-20150252003-A1 Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells COL2A1, MYADM, COL1A1 ATM 2467/4885ALDH1A1 23/4885LMNA 1693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.