Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.79 |
| ▸ | DRD3 | P35462 | 8/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401502 | 0.88 | HTR6 (1.00) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28405325 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2HRH3MEN1 | |
| SCHEMBL28401574 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2HRH3MEN1 | |
| SCHEMBL28397927 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL13892351 | 0.84 | HTR6 (0.90) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28393831 | 0.81 | HTR6 (0.76) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28401494 | 0.81 | HTR6 (0.76) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28888877 | 0.81 | HTR6 (0.76) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL1134887 | 0.80 | HTR6 (0.52) | HTR6DRD3MEN1KMT2A | |
| SCHEMBL5960057 | 0.77 | PDE4A (0.52) | HTR6DRD3DRD2HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367472-B | Indoline derivative and application thereof in medicine | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |