Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.79 |
| ▸ | DRD3 | P35462 | 7/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14401502 | 0.88 | HTR6 (1.00) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28393831 | 0.88 | HTR6 (0.76) | HTR6DRD3DRD2HRH3HTR7 | |
| SCHEMBL28396609 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2MEN1KMT2A | |
| SCHEMBL28405325 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2MEN1KMT2A | |
| SCHEMBL28397927 | 0.88 | HTR6 (0.79) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL13892351 | 0.84 | HTR6 (0.90) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28401291 | 0.81 | HTR6 (0.70) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL5200670 | 0.81 | HTR6 (0.66) | HTR6DRD3DRD2MEN1KMT2A | |
| SCHEMBL28888877 | 0.81 | HTR6 (0.76) | HTR6DRD3DRD2HRH3 | |
| SCHEMBL28401494 | 0.81 | HTR6 (0.76) | HTR6DRD3DRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367472-B | Indoline derivative and application thereof in medicine | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |