Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SREBF2 | Q12772 | 2/20 | 0.44 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13283433 | 0.84 | RAB9A (0.60) | ALDH1A1MAPTHPGDPOLBHSD17B10 | |
| SCHEMBL8989216 | 0.83 | MEN1 (0.43) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL2759538 | 0.83 | CNR2 (0.43) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL29407960 | 0.83 | IRAK4 (0.48) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL16768775 | 0.83 | IRAK4 (0.48) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL13534470 | 0.83 | SCN9A (0.46) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL28888400 | 0.81 | CTSS (0.49) | KDM4ETDP1RAB9AENPP3SMN1; SMN2 | |
| SCHEMBL3421833 | 0.81 | KMT2A (0.59) | SREBF2ALDH1A1MAPTHPGDPOLB | |
| SCHEMBL244011 | 0.81 | CCR1 (0.46) | KDM4ETDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL13658670 | 0.81 | PDE10A (0.51) | MAPTMEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111138346-B | 2-ethyl-4,6-disubstituted pyridine compound and preparation method thereof | 上海大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-111138346-A | 2-ethyl-4, 6-disubstituted pyridine compound and preparation method thereof | 上海大学 | 2020-05-12 | — | — | CN | disclosed |