Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324872 | 0.84 | TSHR (0.48) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL8334403 | 0.79 | ALDH1A1 (0.41) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL11276357 | 0.78 | NPC1 (0.49) | ALDH1A1GLATSHRTP53 | |
| Hydrochloric Acid SCHEMBL11258931 | 0.76 | NPC1 (0.48) | ALDH1A1GLATSHRTP53 | |
| SCHEMBL6136294 | 0.76 | ALDH1A1 (0.45) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL430660 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL430659 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GLATSHRTP53SMN1; SMN2 | |
| SCHEMBL4926088 | 0.74 | LMNA (0.42) | ALDH1A1LMNAMEN1KMT2AATM | |
| SCHEMBL15004705 | 0.74 | HPGD (0.35) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL28571251 | 0.74 | ALDH1A1 (0.44) | ALDH1A1GLATSHRTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111148740-A | Compounds useful as autophagy modulators and methods of making and using the same | 微境生物医药科技(上海)有限公司 | 2020-05-12 | — | — | CN | disclosed |