SCHEMBL28397183

SCHEMBL28397183

Clc1ccc(-c2c[nH]c(-c3ccccn3)n2)c(Cl)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.54
MAPT P10636 3/20 0.54
ALDH1A1 P00352 2/20 0.54
RAB9A P51151 2/20 0.54
PKM P14618 1/20 0.54
GRM5 P41594 1/20 0.53
CBFB Q13951 4/20 0.50
METAP2 P50579 1/20 0.50
METAP1 P53582 1/20 0.50
CCR1 P32246 1/20 0.44
CCR5 P51681 1/20 0.44
CCR8 P51685 1/20 0.44
DCTPP1 Q9H773 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
PPP1CA P62136 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NOTUM Q6P988 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28406315 0.89 CBFB (0.50) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL28632051 0.82 NPC1 (0.43) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL29712861 0.82 NPC1 (0.43) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL7144947 0.82 HSP90AA1 (0.47) MAPTSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL2322004 0.82 NPC1 (0.69) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL31305456 0.81 ALDH1A1 (0.47) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL3135986 0.81 ALDH1A1 (0.47) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL28402325 0.79 GRM5 (0.52) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL4269229 0.79 MAPT (0.41) NPC1MAPTALDH1A1RAB9APKM
SCHEMBL28397335 0.78 CCR1 (0.51) NPC1MAPTRAB9APKMGRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed
CN-111057043-B Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2021-11-02 CN disclosed
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN disclosed