SCHEMBL28397209 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK13	O15264	17/20	0.71

▸	MAPK12	P53778	17/20	0.71

▸	MAPK11	Q15759	17/20	0.71

▸	MAPK14	Q16539	17/20	0.71

▸	RAF1	P04049	11/20	0.71

▸	MAPK9	P45984	1/20	0.70

▸	GCGR	P47871	6/20	0.67

▸	BRAF	P15056	4/20	0.64

▸	BRDT	Q58F21	1/20	0.61

▸	ALOX5	P09917	1/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4413641	0.89	MAPK14 (0.70)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28400755	0.86	BRAF (0.58)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28406419	0.85	MAPK13 (0.70)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL7228717	0.83	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL2949385	0.83	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28410714	0.83	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL14060082	0.82	MAPK13 (0.49)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL5921859	0.81	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL6469111	0.81	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1
SCHEMBL28403334	0.81	MAPK13 (1.00)	MAPK13MAPK12MAPK11MAPK14RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111057043-A	Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method	深圳市贝加电子材料有限公司	2020-04-24	—	—	CN	claimed