SCHEMBL28397221

SCHEMBL28397221

CCO[Si](OCC)(C(C)N)C(N)CC(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
ANPEP P15144 1/20 0.30
ERAP2 Q6P179 1/20 0.30
ERAP1 Q9NZ08 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27829493 0.82
SCHEMBL8004366 0.81 OPRM1 (0.32)
SCHEMBL222216 0.78 OPRM1 (0.34)
SCHEMBL15063382 0.77 TSHR (0.38) ALDH1A1TSHRMAPK1ANPEPERAP2
SCHEMBL28406700 0.73
SCHEMBL249629 0.66 OPRM1 (0.32)
SCHEMBL2715629 0.65 OPRM1 (0.31)
SCHEMBL105907 0.65 LMNA (0.35)
SCHEMBL4817918 0.64
Methylamine SCHEMBL28486504 0.64 OPRM1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111183178-B Method for preparing amino-functional polydiorganosiloxanes using removable acid catalysts 美国陶氏有机硅公司 2022-12-09 CN disclosed
CN-114630857-A Method for producing polyepoxysazanes and for producing aminofunctional polyorganosiloxanes using polyepoxysazanes 美国陶氏有机硅公司 2022-06-14 CN disclosed
CN-111183178-A Method for preparing amino-functional polydiorganosiloxanes using removable acid catalysts 美国陶氏有机硅公司 2020-05-19 CN disclosed