SCHEMBL28397232

SCHEMBL28397232

N=Cc1ccc(NC=O)o1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNA4 P43681 1/20 0.35
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28272953 0.79 ALDH1A1 (0.42) CHRNA4ALDH1A1
SCHEMBL6167528 0.71 CHRNA4 (0.37) CHRNA4ALDH1A1
SCHEMBL15651689 0.71
SCHEMBL6168194 0.70
SCHEMBL6748964 0.68 CHRNA4 (0.36) CHRNA4ALDH1A1
SCHEMBL27637650 0.65 GAA (0.52) CHRNA4ALDH1A1
SCHEMBL6208343 0.63 CHRNA4 (0.35) CHRNA4
SCHEMBL29021883 0.62 ALDH1A1 (0.32) CHRNA4ALDH1A1
SCHEMBL6168602 0.62 SMN1; SMN2 (0.56) CHRNA4ALDH1A1
SCHEMBL8291119 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111194310-B Process for producing 2, 5-bis (aminomethyl) tetrahydrofuran 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-111201221-B Process for producing 2, 5-bis (aminomethyl) tetrahydrofuran 三菱瓦斯化学株式会社 2023-10-24 CN disclosed
CN-111201221-A Method for producing 2, 5-bis (aminomethyl) tetrahydrofuran 三菱瓦斯化学株式会社 2020-05-26 CN disclosed
CN-111194310-A Method for producing 2, 5-bis (aminomethyl) tetrahydrofuran 三菱瓦斯化学株式会社 2020-05-22 CN disclosed