SCHEMBL6167528

SCHEMBL6167528

CNc1ccc(NC=O)o1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNA4 P43681 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28272953 0.90 ALDH1A1 (0.42) CHRNA4ALDH1A1LMNA
SCHEMBL8127892 0.79
SCHEMBL6168194 0.74
SCHEMBL27637650 0.74 GAA (0.52) CHRNA4ALDH1A1LMNA
SCHEMBL6748964 0.73 CHRNA4 (0.36) CHRNA4ALDH1A1
SCHEMBL6208343 0.71 CHRNA4 (0.35) CHRNA4
SCHEMBL28397232 0.71 CHRNA4 (0.35) CHRNA4ALDH1A1
SCHEMBL6167149 0.67 ALOX15 (0.31)
SCHEMBL6168602 0.66 SMN1; SMN2 (0.56) CHRNA4ALDH1A1LMNA
SCHEMBL29021883 0.66 ALDH1A1 (0.32) CHRNA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498109-A1 Furan derivatives and dyeing composition comprising a furan derivative as coupler L'OREAL (FR) 2005-01-19 EP claimed
EP-1498109-A1 Furan derivatives and dyeing composition comprising a furan derivative as coupler L'OREAL (FR) 2005-01-19 EP disclosed