Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13307575 | 0.87 | POLB (0.53) | SRCNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13172900 | 0.86 | SRC (0.52) | SRCHTTMAPK14SMN1; SMN2HDAC3 | |
| SCHEMBL22959003 | 0.86 | SRC (0.58) | SRCNPC1RAB9AMEN1KMT2A | |
| SCHEMBL5328882 | 0.85 | CYP1A2 (0.59) | SRCNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16280384 | 0.84 | SRC (0.54) | SRCNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25382666 | 0.82 | MAPK14 (0.49) | SRCMEN1KMT2AMAPK14ALDH1A1 | |
| SCHEMBL26328679 | 0.81 | SRC (0.62) | SRCNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15474950 | 0.81 | MAPK14 (0.44) | SRCHTTMAPK14TSHRALDH1A1 | |
| SCHEMBL13117237 | 0.81 | ALDH1A1 (0.54) | SRCHTTRAB9AMAPK14TSHR | |
| SCHEMBL11815716 | 0.81 | SRC (0.61) | SRCNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057015-A | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2020-04-24 | — | — | CN | claimed |
| CN-111057015-B | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-111057015-A | 2- (4-phenyl-1H-1, 2, 3-triazole-1-yl) acetic acid and acethydrazide compounds | 中国医科大学 | 2020-04-24 | — | — | CN | disclosed |