SCHEMBL28397353

SCHEMBL28397353

Clc1ccc(Cl)c(-c2c[nH]c(Cc3cc[nH]c3)n2)c1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
ALDH1A1 P00352 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
HTR2B P41595 1/20 0.34
PDE4D Q08499 1/20 0.34
RORC P51449 3/20 0.33
AGPAT2 O15120 1/20 0.33
CXCR2 P25025 1/20 0.33
PTPN1 P18031 1/20 0.33
PDE2A O00408 1/20 0.32
AR P10275 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28406340 0.90 HSP90AA1 (0.39) CXCR2
SCHEMBL2868906 0.86 IDO1 (0.42) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL28812735 0.85 IDO1 (0.41) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL26110557 0.84 CXCR2 (0.45) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL27967661 0.84 ADORA2A (0.41) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL28399055 0.83 RAB9A (0.40) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL28397356 0.81 KMO (0.36) CXCR2
SCHEMBL27967894 0.81 IDO1 (0.42) IDO1ALDH1A1RXFP1HTR2BPDE4D
SCHEMBL28406402 0.80 CXCR2 (0.32) CXCR2
SCHEMBL27967694 0.80 SMN1; SMN2 (0.42) IDO1ALDH1A1RXFP1HTR2BPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-B Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2021-11-02 CN claimed
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed