Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.67 |
| ▸ | CASP2 | P42575 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | CASP6 | P55212 | 1/20 | 0.67 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | MITF | O75030 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401107 | 0.94 | MAPT (0.62) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL28396223 | 0.89 | CASP3 (0.65) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL29664268 | 0.86 | HPGD (0.58) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL28394913 | 0.86 | HPGD (0.58) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL23898948 | 0.82 | KMT2A (0.83) | MAPTPOLBMITFMAPK1MEN1 | |
| SCHEMBL9134339 | 0.82 | KMT2A (0.83) | MAPTPOLBMITFMAPK1MEN1 | |
| SCHEMBL8572381 | 0.82 | KMT2A (0.83) | MAPTPOLBMITFMAPK1MEN1 | |
| SCHEMBL28888814 | 0.81 | POLB (0.63) | MAPTPOLBMEN1KMT2ARAB9A | |
| SCHEMBL12218318 | 0.81 | MEN1 (0.82) | MAPTPOLBMITFMAPK1PSMB5 | |
| SCHEMBL12857744 | 0.80 | CASP3 (1.00) | CASP3CASP2CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040159-A | High-barrier polyimide containing high-planarity structure and preparation method and application thereof | 湖南工业大学 | 2020-04-21 | — | — | CN | disclosed |