Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 3/20 | 0.65 |
| ▸ | CASP2 | P42575 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | CASP6 | P55212 | 1/20 | 0.65 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401107 | 0.96 | MAPT (0.62) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL28397382 | 0.89 | CASP3 (0.67) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL28432062 | 0.87 | CASP3 (0.57) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL23898948 | 0.83 | KMT2A (0.83) | MEN1KMT2ARAB9ANPC1MITF | |
| SCHEMBL9134339 | 0.83 | KMT2A (0.83) | MEN1KMT2ARAB9ANPC1MITF | |
| SCHEMBL8572381 | 0.83 | KMT2A (0.83) | MEN1KMT2ARAB9ANPC1MITF | |
| SCHEMBL28068279 | 0.82 | MEN1 (0.58) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL28068281 | 0.79 | MEN1 (0.70) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL12857744 | 0.79 | CASP3 (1.00) | CASP3CASP2CASP7CASP6CASP8 | |
| SCHEMBL13442880 | 0.79 | CASP3 (1.00) | CASP3CASP2CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111040159-A | High-barrier polyimide containing high-planarity structure and preparation method and application thereof | 湖南工业大学 | 2020-04-21 | — | — | CN | disclosed |