Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28397965 | 0.75 | SLC22A12 (0.35) | SSTR4SLC22A12 | |
| SCHEMBL183109 | 0.74 | NUDT1 (0.39) | SSTR4NUDT1HTR2APKLRTNKS | |
| SCHEMBL6370683 | 0.73 | NUDT1 (0.42) | SSTR4NUDT1TNKSMEN1KMT2A | |
| SCHEMBL19456738 | 0.70 | SLC22A12 (0.47) | SLC22A12 | |
| SCHEMBL28396551 | 0.69 | SLC22A12 (0.44) | NTRK1SLC22A12AURKADAPK3JAK2 | |
| SCHEMBL1419899 | 0.67 | KDM4E (0.50) | NUDT1HTR2AHTR2CKCNH2SLC22A12 | |
| SCHEMBL12540739 | 0.67 | KDM4E (0.47) | NUDT1HTR2AHTR2CKCNH2 | |
| SCHEMBL259658 | 0.67 | NUDT1 (0.42) | NUDT1NTRK1CLK4HSD11B1MEN1 | |
| SCHEMBL8313115 | 0.66 | HTR2A (0.43) | SSTR4NUDT1HTR2AHTR2CKCNH2 | |
| Lithium SCHEMBL31115344 | 0.66 | DHODH (0.49) | NUDT1HTR2AHTR2CKCNH2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107683282-B | URAT1 inhibitor and application thereof in medicine | 江苏新元素医药科技有限公司 | 2020-05-22 | — | — | CN | claimed |
| CN-107683282-B | URAT1 inhibitor and application thereof in medicine | 江苏新元素医药科技有限公司 | 2020-05-22 | — | — | CN | disclosed |