Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.84 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.84 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.84 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.84 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.84 |
| ▸ | SRC | P12931 | 2/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.84 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.80 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.79 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.79 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.79 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.79 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.75 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.75 |
| ▸ | LDHA | P00338 | 1/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.75 |
| ▸ | FBP1 | P09467 | 1/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Triphosphate SCHEMBL1496208 | 0.96 | P2RY1 (0.89) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Triphosphate SCHEMBL29467395 | 0.96 | P2RY1 (0.89) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Diphosphate SCHEMBL30929365 | 0.95 | P2RY1 (0.87) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Diphosphate SCHEMBL4406433 | 0.95 | P2RY1 (0.87) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Diphosphate SCHEMBL5498270 | 0.95 | P2RY1 (0.87) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Diphosphate SCHEMBL31158049 | 0.95 | P2RY1 (0.87) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Triphosphate SCHEMBL13722152 | 0.95 | P2RY1 (0.94) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL376008 | 0.95 | P2RY1 (0.94) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| SCHEMBL9171542 | 0.95 | P2RY1 (0.94) | P2RY1P2RX1P2RX3P2RY2P2RX2 | |
| Adenosine Triphosphate SCHEMBL2227081 | 0.95 | P2RY1 (0.94) | P2RY1P2RX1P2RX3P2RY2P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111157724-A | Phosphocreatine kinase isoenzyme detection kit | 上海高踪医疗器械科技有限公司 | 2020-05-15 | — | — | CN | disclosed |