Adenosine Diphosphate

Adenosine Diphosphate

SCHEMBL4406433

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)([O-])O)[C@@H](O)[C@H]1O.[K+]

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Adenosine Diphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 10/20 0.87
P2RY2 P41231 3/20 0.87
P2RX1 P51575 2/20 0.87
P2RX3 P56373 2/20 0.87
ALDH1A1 P00352 2/20 0.87
SRC P12931 2/20 0.87
SMN1; SMN2 Q16637 2/20 0.87
P2RX4 Q99571 1/20 0.87
P2RX2 Q9UBL9 1/20 0.87
TRPM2 O94759 2/20 0.81
MACROD2 A1Z1Q3 1/20 0.81
SIRT6 Q8N6T7 1/20 0.81
MACROD1 Q9BQ69 1/20 0.81
TAS1R3 Q7RTX0 2/20 0.77
TAS1R1 Q7RTX1 2/20 0.77
P2RY11 Q96G91 2/20 0.77
DNPH1 O43598 1/20 0.77
PRKAB2 O43741 1/20 0.77
LDHA P00338 1/20 0.77
ADRB2 P07550 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Diphosphate SCHEMBL31158049 0.98 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL30929365 0.98 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL5498270 0.98 P2RY1 (0.87) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29467395 0.97 P2RY1 (0.89) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL1496208 0.97 P2RY1 (0.89) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Diphosphate SCHEMBL28397752 0.95 P2RY1 (0.84) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL3040412 0.95 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL19947525 0.94 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL29573857 0.94 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1
Adenosine Triphosphate SCHEMBL574960 0.94 P2RY1 (0.83) P2RY1P2RY2P2RX1P2RX3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255291-B1 MIXTURE OF ALANINE, ADENOSINE COMPOUND, RIBOSE COMPOUND, ASCORBIC ACID AND NICOTINIC ACID PEREGRINE PHARMACEUTICALS, INC. 2001-07-03 US claimed
US-20120156278-A1 SYSTEMS AND METHODS FOR PREPARING AUTOLOGOUS FIBRIN GLUE CASCADE MEDICAL ENTERPRISES, LLC (US) 2012-06-21 US disclosed
US-20090258056-A1 SYSTEMS AND METHODS FOR PREPARING AUTOLOGOUS FIBRIN GLUE CASCADE MEDICAL ENTERPRISES, LLC (US) 2009-10-15 US disclosed
US-20080199513-A1 SYSTEMS AND METHODS FOR PREPARING AUTOLOGOUS FIBRIN GLUE CASCADE MEDICAL ENTERPRISES, LLC (US) 2008-08-21 US disclosed
US-6255291-B1 MIXTURE OF ALANINE, ADENOSINE COMPOUND, RIBOSE COMPOUND, ASCORBIC ACID AND NICOTINIC ACID PEREGRINE PHARMACEUTICALS, INC. 2001-07-03 US disclosed
EP-0967984-A1 COMPOSITION AND METHOD FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS RESULTING IN CHRONIC CONDITIONS Peregrine Pharmaceutical, Inc. (US) 2000-01-05 EP disclosed
WO-1998046206-A1 SKIN CREAM COMPOSITION PEREGRINE PHARMACEUTICAL, INC. (US) 1998-10-22 WO disclosed
WO-1998039013-A1 COMPOSITION AND METHOD FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS RESULTING IN CHRONIC CONDITIONS PEREGRINE PHARMACEUTICAL, INC. (US) 1998-09-11 WO disclosed