Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.43 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30546929 | 1.00 | RECQL (0.48) | RECQLAKR1C3AKR1C2SMN1; SMN2NR3C1 | |
| SCHEMBL29047686 | 0.89 | LMNA (0.49) | RECQLTAS2R14RXFP1LMNAMAPT | |
| SCHEMBL30546976 | 0.89 | LMNA (0.49) | RECQLTAS2R14RXFP1LMNAMAPT | |
| SCHEMBL28397884 | 0.88 | RECQL (0.60) | RECQLTP53RXFP1ALDH1A1LMNA | |
| SCHEMBL30546971 | 0.88 | MAPK14 (0.48) | NR3C1RXFP1ALDH1A1LMNAMAPT | |
| SCHEMBL29047655 | 0.88 | MAPK14 (0.48) | NR3C1RXFP1ALDH1A1LMNAMAPT | |
| SCHEMBL29047658 | 0.87 | RXFP1 (0.57) | SMN1; SMN2TAS2R14RXFP1ALDH1A1MAPT | |
| SCHEMBL30546927 | 0.87 | RXFP1 (0.57) | SMN1; SMN2TAS2R14RXFP1ALDH1A1MAPT | |
| SCHEMBL30546950 | 0.86 | CLCN2 (0.51) | RECQLTAS2R14RXFP1HTTALDH1A1 | |
| SCHEMBL29047622 | 0.86 | CLCN2 (0.51) | RECQLTAS2R14RXFP1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535357-A | Arylamino benzamide derivative containing substituted pyrazole structure, preparation method and application | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |