SCHEMBL28398017

SCHEMBL28398017

Cc1[nH]c(Cc2ccncc2)nc1-c1ccc(Cl)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 2/20 0.44
DBF4 Q9UBU7 2/20 0.44
CCNE1 P24864 2/20 0.43
CDK2 P24941 2/20 0.43
CCNB2 O95067 1/20 0.43
CCNE2 O96020 1/20 0.43
CDK1 P06493 1/20 0.43
CDK4 P11802 1/20 0.43
CCNB1 P14635 1/20 0.43
CCND1 P24385 1/20 0.43
CCNB3 Q8WWL7 1/20 0.43
CRHR1 P34998 7/20 0.41
EGFR P00533 2/20 0.38
ERBB2 P04626 2/20 0.38
GCGR P47871 1/20 0.38
MAPK14 Q16539 1/20 0.38
HTT P42858 1/20 0.37
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD11B1 P28845 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29889804 0.91 PRNP (0.44) CRHR1EGFRERBB2HSD11B1
SCHEMBL2870075 0.91 PRNP (0.44) CRHR1EGFRERBB2HSD11B1
SCHEMBL28406049 0.90 CCNB2 (0.40) CDC7DBF4CCNE1CDK2CCNB2
SCHEMBL1747656 0.88 CRHR1 (0.44) CCNE1CDK2CCNB2CCNE2CDK1
SCHEMBL31305532 0.88 CRHR1 (0.44) CCNE1CDK2CCNB2CCNE2CDK1
SCHEMBL26112642 0.88 DPP4 (0.44) CRHR1EGFRERBB2KMT2AHSD11B1
SCHEMBL28813824 0.86 CRHR1 (0.40) CRHR1EGFRERBB2HSD11B1
SCHEMBL13476252 0.86 CCNE2 (0.43) CDC7DBF4CCNE1CDK2CCNE2
SCHEMBL26111210 0.86 CNR1 (0.46) CRHR1EGFRERBB2GCGRMAPK14
SCHEMBL2868908 0.85 AHR (0.41) CRHR1EGFRERBB2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN claimed
CN-111057043-B Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2021-11-02 CN disclosed
CN-111057043-A Imidazole compound, preparation method and application thereof, organic weldable protective agent containing imidazole compound and surface treatment method 深圳市贝加电子材料有限公司 2020-04-24 CN disclosed