Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398482 | 1.00 | LMNA (0.31) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28873895 | 0.83 | HIF1A (0.36) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28873896 | 0.83 | HIF1A (0.36) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29231774 | 0.82 | CHRM2 (0.31) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28236475 | 0.78 | LMNA (0.35) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28889722 | 0.76 | SCN9A (0.32) | — | |
| SCHEMBL28407622 | 0.76 | SMYD3 (0.36) | LMNATSHRMAPT | |
| SCHEMBL28407625 | 0.76 | SMYD3 (0.36) | LMNATSHRMAPT | |
| SCHEMBL1861685 | 0.75 | ADAM17 (0.30) | — | |
| SCHEMBL1861689 | 0.75 | ADAM17 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225900-A | 3, 4-disubstituted 3-cyclobutene-1, 2-diones and their use | 阿勒根公司 | 2020-06-02 | — | — | CN | disclosed |