Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 3/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15696739 | 0.84 | MAPT (0.57) | MEN1MAPTKMT2AKCNJ5KCNJ3 | |
| SCHEMBL28185436 | 0.82 | MEN1 (0.61) | MEN1MAPTKMT2ANLRP3KCNJ5 | |
| SCHEMBL5982854 | 0.78 | ERCC1 (0.40) | GRM5LMNAPTGES | |
| SCHEMBL5102126 | 0.77 | NLRP3 (0.76) | MEN1MAPTKMT2ANLRP3KCNJ5 | |
| SCHEMBL16254749 | 0.77 | MKNK2 (0.60) | MAPTHTT | |
| SCHEMBL16236896 | 0.76 | MEN1 (0.65) | MEN1MAPTKMT2ANLRP3KCNJ5 | |
| SCHEMBL27499406 | 0.75 | CSNK1D (0.62) | MEN1MAPTKMT2ANLRP3HTT | |
| SCHEMBL3446231 | 0.75 | FFAR1 (0.49) | MAPTLMNAALDH1A1PTGES | |
| SCHEMBL15687844 | 0.74 | MAPT (0.57) | MEN1MAPTKMT2AHTTLMNA | |
| SCHEMBL28027717 | 0.73 | GRM5 (0.39) | GRM5ALDH1A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107344940-B | BTK inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-04-21 | — | — | CN | disclosed |