Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027717 | 0.88 | GRM5 (0.39) | FFAR1CYP1A2CYP2C19NFKB1ALDH1A1 | |
| SCHEMBL5982854 | 0.85 | ERCC1 (0.40) | FFAR1PTGESLMNA | |
| SCHEMBL4542339 | 0.83 | FFAR1 (0.70) | FFAR1CYP1A2CYP2C19AKR1B1PTGES | |
| SCHEMBL3351697 | 0.81 | FFAR1 (0.48) | FFAR1TSHR | |
| SCHEMBL21836127 | 0.81 | PTGS1 (0.53) | FFAR1AKR1B1GAATSHRNFKB1 | |
| SCHEMBL4945455 | 0.81 | HDAC4 (0.39) | FFAR1PTGESGABRA1GABRG2GABRB3 | |
| SCHEMBL8850812 | 0.80 | HRH3 (0.47) | PTGES | |
| SCHEMBL27032998 | 0.80 | NPC1 (0.43) | FFAR1ALDH1A1PTGESHPGD | |
| SCHEMBL1559856 | 0.80 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL3447198 | 0.80 | FFAR1 (0.65) | FFAR1AKR1B1GAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |