Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238053 | 0.91 | NPSR1 (0.50) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17720334 | 0.82 | LMNA (0.49) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17722765 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL19366492 | 0.81 | LMNA (0.47) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL3238689 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL1377763 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL7772943 | 0.79 | NPSR1 (0.42) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17720348 | 0.79 | LMNA (0.49) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL2035293 | 0.75 | LMNA (0.69) | LMNASMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL28790808 | 0.74 | LMNA (0.59) | LMNASMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051325-B | Spirothiocyclobutane nucleosides | 詹森药业有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-111051325-A | Spirothiacyclobutanenucleosides | 詹森药业有限公司 | 2020-04-21 | — | — | CN | disclosed |