Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.85 |
| ▸ | AXL | P30530 | 3/20 | 0.73 |
| ▸ | FLT3 | P36888 | 3/20 | 0.72 |
| ▸ | KIT | P10721 | 2/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.72 |
| ▸ | KDR | P35968 | 2/20 | 0.72 |
| ▸ | MST1R | Q04912 | 2/20 | 0.72 |
| ▸ | PLK4 | O00444 | 1/20 | 0.72 |
| ▸ | STK25 | O00506 | 1/20 | 0.72 |
| ▸ | CIT | O14578 | 1/20 | 0.72 |
| ▸ | AURKA | O14965 | 1/20 | 0.72 |
| ▸ | CHUK | O15111 | 1/20 | 0.72 |
| ▸ | MUSK | O15146 | 1/20 | 0.72 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.72 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.72 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.72 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.72 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.72 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401426 | 0.95 | MET (0.79) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28408302 | 0.94 | MET (0.90) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28398179 | 0.94 | MET (0.87) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28407173 | 0.94 | MET (0.91) | METFLT3KITPDGFRAKDR | |
| SCHEMBL15262332 | 0.93 | MET (0.76) | METAXLFLT3KITPDGFRA | |
| SCHEMBL28403182 | 0.93 | MET (0.88) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28403285 | 0.93 | MET (0.86) | METAXLFLT3KITPDGFRA | |
| SCHEMBL28403331 | 0.92 | MET (1.00) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28889594 | 0.91 | MET (0.88) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28411232 | 0.89 | MET (1.00) | METFLT3KITPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474039-B | 4-phenoxy substituted quinoline compound containing triazazolone and imidazole and application thereof | 沈阳药科大学 | 2020-05-01 | — | — | CN | claimed |
| CN-107474039-B | 4-phenoxy substituted quinoline compound containing triazazolone and imidazole and application thereof | 沈阳药科大学 | 2020-05-01 | — | — | CN | disclosed |