Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.86 |
| ▸ | FLT3 | P36888 | 2/20 | 0.68 |
| ▸ | KIT | P10721 | 1/20 | 0.68 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | MST1R | Q04912 | 1/20 | 0.68 |
| ▸ | AXL | P30530 | 1/20 | 0.64 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28403180 | 0.95 | MET (0.89) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28403297 | 0.94 | MET (0.89) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28401327 | 0.94 | MET (0.88) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28399679 | 0.93 | MET (0.85) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28407223 | 0.92 | MET (1.00) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28401426 | 0.92 | MET (0.79) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28403182 | 0.89 | MET (0.88) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28403694 | 0.88 | MET (0.90) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28411232 | 0.88 | MET (1.00) | METFLT3KITPDGFRAKDR | |
| SCHEMBL28408302 | 0.87 | MET (0.90) | METFLT3KITPDGFRAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474039-B | 4-phenoxy substituted quinoline compound containing triazazolone and imidazole and application thereof | 沈阳药科大学 | 2020-05-01 | — | — | CN | claimed |
| CN-107474039-B | 4-phenoxy substituted quinoline compound containing triazazolone and imidazole and application thereof | 沈阳药科大学 | 2020-05-01 | — | — | CN | disclosed |