Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277560 | 0.83 | KMT2A (0.68) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28403540 | 0.83 | F10 (0.77) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28346556 | 0.80 | KMT2A (0.72) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28189189 | 0.79 | KMT2A (0.76) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28399871 | 0.78 | KMT2A (0.69) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28278988 | 0.78 | L3MBTL1 (0.73) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28277563 | 0.77 | KMT2A (0.64) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL23657637 | 0.77 | HDAC1 (0.72) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL97400 | 0.77 | KMT2A (0.68) | KMT2ATP53NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28349237 | 0.77 | TP53 (0.68) | KMT2ATP53NPSR1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191737-B | Process for producing N- (2-methylthiophenyl) isoindole-1, 3-dione compound | 温州大学 | 2020-04-21 | — | — | CN | disclosed |