Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400900 | 0.91 | GPR119 (0.52) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL28397493 | 0.91 | GPR119 (0.52) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL28397494 | 0.91 | GPR119 (0.52) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL5239182 | 0.88 | GPR119 (0.63) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL20305694 | 0.85 | MAPT (0.56) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL20305696 | 0.85 | MAPT (0.56) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL23410150 | 0.84 | GPR119 (0.61) | LMNAGPR119SMN1; SMN2USP2 | |
| SCHEMBL15749513 | 0.84 | GPR119 (0.56) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL5272983 | 0.83 | GPR119 (0.55) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL8226799 | 0.83 | GPR119 (0.53) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111072675-A | Nitrogen-containing fused tricyclic derivatives and uses thereof | 广东东阳光药业有限公司 | 2020-04-28 | — | — | CN | disclosed |