Orthocresol

Orthocresol

SCHEMBL28401339

Cc1cccc(C)c1OP(=O)(O)Oc1c(C)cccc1C.Cc1ccccc1O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.41
ATM Q13315 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
HSD17B10 Q99714 2/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272850 0.89 INPPL1 (0.43) KMT2AMEN1LMNAHSD17B10ALDH1A1
Hydroquinone SCHEMBL2549100 0.85 SCN8A (0.40) CYP1A2CYP2C19KMT2AMEN1ESR1
Biphenyl SCHEMBL7632006 0.84 GPR84 (0.44) KMT2AMEN1HSD17B10ALDH1A1SMN1; SMN2
Toluene SCHEMBL29065788 0.84 ACP3 (0.41) KMT2AMEN1LMNAHSD17B10TSHR
SCHEMBL6563116 0.82 SRC (0.52) KMT2AMEN1LMNAALDH1A1SMN1; SMN2
Orthocresol SCHEMBL866537 0.82 SRC (0.52) CYP2C19KMT2AMEN1LMNAALDH1A1
Orthocresol SCHEMBL456320 0.82 SRC (0.52) CYP2C19KMT2AMEN1LMNAALDH1A1
SCHEMBL27572156 0.82 INPPL1 (0.44) CYP1A2CYP2C19KMT2AMEN1LMNA
Resorcinol SCHEMBL1013060 0.82 CYP3A4 (0.43) ATMCYP1A2CYP2C19KMT2AMEN1
SCHEMBL3842119 0.81 CES2 (0.46) ATMCYP2C19LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111051420-B Thermoplastic resin composition and molded article formed from the same 株式会社TBM 2023-02-10 CN disclosed
CN-111051420-A Thermoplastic resin composition and molded article formed from the same 株式会社TBM 2020-04-21 CN disclosed