Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30435963 | 1.00 | BTN3A1 (0.41) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL20845948 | 1.00 | BTN3A1 (0.41) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL29692333 | 1.00 | BTN3A1 (0.41) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL23044633 | 0.91 | MEN1 (0.39) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL28986476 | 0.88 | BTN3A1 (0.41) | BTN3A1KDM4EALDH1A1OGG1HTT | |
| SCHEMBL29895522 | 0.88 | BTN3A1 (0.41) | BTN3A1KDM4EALDH1A1OGG1HTT | |
| SCHEMBL20840403 | 0.88 | ALDH1A1 (0.39) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL21192831 | 0.88 | ALDH1A1 (0.39) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL23827926 | 0.88 | ALDH1A1 (0.39) | BTN3A1KDM4EALDH1A1PGRGAA | |
| SCHEMBL28529772 | 0.88 | ALDH1A1 (0.39) | BTN3A1KDM4EALDH1A1PGRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111194217-B | 4 '-fluoro-2' -methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication | 里伯赛恩斯有限责任公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-111194217-A | 4 '-fluoro-2' -methyl substituted nucleoside derivatives as inhibitors of HCV RNA replication | 里伯赛恩斯有限责任公司 | 2020-05-22 | — | — | CN | disclosed |