Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404470 | 0.91 | ADRB2 (0.39) | HTTKMT2AADRB2TNF | |
| SCHEMBL28401918 | 0.85 | ALDH1A1 (0.35) | ALDH1A1POLBKMT2AGSK3B | |
| SCHEMBL29219620 | 0.82 | KCNH2 (0.38) | ALDH1A1POLBKMT2AGSK3B | |
| SCHEMBL28408025 | 0.82 | KCNH2 (0.36) | POLB | |
| SCHEMBL605767 | 0.78 | ADRB2 (0.41) | ALDH1A1POLBADRB2GSK3B | |
| SCHEMBL536999 | 0.77 | ADRB2 (0.40) | POLBADRB2GSK3B | |
| SCHEMBL729612 | 0.75 | ADRB2 (0.39) | ALDH1A1POLBADRB2GSK3B | |
| SCHEMBL606988 | 0.74 | ADRB2 (0.38) | ADRB2GSK3B | |
| SCHEMBL3337171 | 0.71 | KCNH2 (0.41) | ALDH1A1POLBKMT2AGSK3B | |
| SCHEMBL31619099 | 0.71 | ADRB2 (0.52) | ALDH1A1LMNAPOLBKMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170941-B | Preparation method of 1-cyclopropyl-6, 7-difluoro-8-methoxy fluoroquinolone-3-carboxylic acid ester | 江西农业大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-111170941-A | Preparation method of 1-cyclopropyl-6, 7-difluoro-8-methoxy fluoroquinolone-3-carboxylic ester | 江西农业大学 | 2020-05-19 | — | — | CN | disclosed |