⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204586 | 0.68 | RAB9A (0.55) | — | |
| SCHEMBL3293293 | 0.67 | MAPT (0.39) | — | |
| SCHEMBL11745018 | 0.63 | MAPT (0.34) | — | |
| SCHEMBL446321 | 0.63 | — | — | |
| SCHEMBL2044209 | 0.62 | — | — | |
| SCHEMBL2726010 | 0.62 | — | — | |
| SCHEMBL11850357 | 0.62 | — | — | |
| SCHEMBL3293694 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL3296075 | 0.58 | ALDH1A1 (0.36) | — | |
| SCHEMBL3294386 | 0.58 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113825543-A | Anthelmintic aza-benzothiophene and aza-benzofuran compounds | 勃林格殷格翰动物保健美国公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113260419-A | Indazolyl cyanoethylamino compounds, compositions thereof, methods of making the same, and methods of using the same | 勃林格殷格翰动物保健美国公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-110381738-B | Pesticidal and parasiticidal vinyl isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-112996788-A | Anthelmintic heterocyclic compounds | 勃林格殷格翰动物保健美国公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-107427496-B | Long-acting injectable formulations comprising isoxazoline active agents, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-107428764-B | 2- (hetero) aryl-substituted fused bicyclic heterocyclic derivatives as pest control agents | 拜耳作物科学股份公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111511741-A | Heterocyclic compound and noxious arthropod control agent containing same | 住友化学株式会社 | 2020-08-07 | — | — | CN | disclosed |
| CN-106943399-B | Parasiticidal compositions comprising isoxazoline active agents, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-106474120-B | Parasiticidal compositions comprising isoxazoline active agents, methods and uses thereof | 勃林格殷格翰动物保健美国公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-111194316-A | Pesticidal and parasiticidal pyrazole-isoxazoline compounds | 勃林格殷格翰动物保健美国公司 | 2020-05-22 | — | — | CN | disclosed |