Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2 | P11137 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402284 | 0.85 | CNR1 (0.51) | MAP2KDM4EKMT2AMAPTALDH1A1 | |
| SCHEMBL28402305 | 0.85 | GAA (0.49) | KDM4EPTGS1PTGS2KMT2AMAPT | |
| SCHEMBL28890620 | 0.85 | MEN1 (0.45) | MAP2KDM4EKMT2AMAPTEGFR | |
| SCHEMBL28404248 | 0.85 | EGFR (0.48) | KDM4EDRD2DRD4DRD3KMT2A | |
| SCHEMBL28890069 | 0.85 | EGFR (0.46) | KDM4EPTGS1PTGS2KMT2AMAPT | |
| SCHEMBL28402205 | 0.84 | EGFR (0.52) | KDM4EKMT2AMAPTEGFRSRC | |
| SCHEMBL9017489 | 0.84 | PTGS1 (0.61) | MAP2KDM4EPTGS1PTGS2DRD2 | |
| SCHEMBL28404610 | 0.82 | PTGS1 (0.48) | KDM4EPTGS1PTGS2KMT2AMAPT | |
| SCHEMBL28402854 | 0.75 | GPR17 (0.52) | KDM4EPTGS2KMT2AMAPTTUBB4A | |
| SCHEMBL6168700 | 0.73 | PTGS2 (0.58) | KDM4EPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217736-B | Method for synthesizing 2-acylindole compound under photocatalysis | 陕西科技大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-111217736-A | Method for synthesizing 2-acylindole compound under photocatalysis | 陕西科技大学 | 2020-06-02 | — | — | CN | disclosed |