Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402205 | 0.89 | EGFR (0.52) | EGFRSRCALDH1A1HPGDKDM4E | |
| SCHEMBL28401795 | 0.85 | MAP2 (0.46) | EGFRSRCSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28402324 | 0.84 | EGFR (0.45) | EGFRSRCALDH1A1KDM4EFOLH1 | |
| SCHEMBL2012674 | 0.79 | KDM4E (0.61) | EGFRSRCALDH1A1HPGDKDM4E | |
| SCHEMBL28404662 | 0.77 | KMT2A (0.50) | EGFRSRCSMN1; SMN2KDM4EHTT | |
| SCHEMBL28402305 | 0.75 | GAA (0.49) | EGFRSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL28890620 | 0.75 | MEN1 (0.45) | EGFRSRCALDH1A1HPGDKDM4E | |
| SCHEMBL28402284 | 0.75 | CNR1 (0.51) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL28890069 | 0.75 | EGFR (0.46) | EGFRHPGDKDM4EMEN1KMT2A | |
| SCHEMBL9503673 | 0.75 | KDM4E (0.52) | EGFRSRCALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217736-B | Method for synthesizing 2-acylindole compound under photocatalysis | 陕西科技大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-111217736-A | Method for synthesizing 2-acylindole compound under photocatalysis | 陕西科技大学 | 2020-06-02 | — | — | CN | disclosed |