SCHEMBL28403238

SCHEMBL28403238

C=CC=CC=CC(=O)NN

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18019256 0.90
SCHEMBL5698674 0.90
SCHEMBL11816978 0.84 MAOB (0.39) ALDH1A1KDM4EGAAMAPTL3MBTL1
SCHEMBL11051266 0.84 MAOB (0.39) ALDH1A1KDM4EGAAMAPTL3MBTL1
Maleic Hydrazide SCHEMBL10745257 0.75 ALDH1A1 (0.42) ALDH1A1KDM4EGAAMAPTL3MBTL1
SCHEMBL11816982 0.75 TSHR (0.40) ALDH1A1KDM4EGAAMAPTL3MBTL1
SCHEMBL1149797 0.73
SCHEMBL1149798 0.73
Maleic Hydrazide SCHEMBL466482 0.73 CYP1A2 (0.44) ALDH1A1KDM4EGAAMAPTL3MBTL1
Maleic Hydrazide SCHEMBL1534936 0.73 CYP1A2 (0.44) ALDH1A1KDM4EGAAMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406373-A Boron-containing diacylhydrazine compounds 英特瑞克斯顿股份有限公司 2017-11-28 CN claimed
CN-107406373-B Boron-containing diacylhydrazine compounds 英特瑞克斯顿股份有限公司 2020-04-28 CN disclosed
CN-107406373-A Boron-containing diacylhydrazine compounds 英特瑞克斯顿股份有限公司 2017-11-28 CN disclosed