Maleic Hydrazide

Maleic Hydrazide

SCHEMBL466482

NNC(=O)C=CC(=O)NN

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
THPO P40225 1/20 0.44
LMNA P02545 1/20 0.41
ALDH1A1 P00352 4/20 0.39
GAA P10253 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HIF1A Q16665 1/20 0.35
GFER P55789 1/20 0.32
POLB P06746 1/20 0.31
CTSD P07339 1/20 0.30
KDM5C P41229 1/20 0.30
PHF8 Q9UPP1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30
KEAP1 Q14145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Hydrazide SCHEMBL55070 1.00 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL28265377 1.00 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL1534936 1.00 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL408266 0.96 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL9489247 0.96 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL7116620 0.96 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL30239213 0.96 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL8367459 0.96 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL28280739 0.93 CYP1A2 (0.39) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL55072 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535795-B High-elasticity self-repairing mechanical color-changing ionic gel film and preparation method thereof 大连理工大学 2026-05-19 CN claimed
CN-119899352-B Room-temperature high-efficiency self-repairing aqueous polyurethane elastomer and preparation method and application thereof 华南理工大学 2026-05-12 CN claimed
US-20260109865-A1 WATER-BORNE COATING COMPOSITION AXALTA COATING SYSTEMS IP CO., LLC (US) 2026-04-23 US claimed
CN-116688209-B Medical dressing, preparation method and application 江南大学 2025-06-24 CN claimed
CN-119899352-A Room-temperature high-efficiency self-repairing aqueous polyurethane elastomer and preparation method and application thereof 华南理工大学 2025-04-29 CN claimed
CN-119812514-A Self-adaptive active regeneration zinc cathode-electrolyte interface stabilization method 广西大学 2025-04-11 CN claimed
CN-119799293-A Thickener composition, thickener, preparation method and application of thickener 中国石油天然气集团有限公司 2025-04-11 CN claimed
CN-119662107-A Strip-type coating method thermal sealing cover tape and preparation method thereof 江西若邦科技股份有限公司 2025-03-21 CN claimed
CN-119674192-A PVDF-based organic-inorganic composite polymer solid electrolyte and preparation method and application thereof 山东创鲁先进电池科技有限公司 2025-03-21 CN claimed
CN-119592014-A Epoxy resin-added curing crosslinking rubber and preparation method thereof 泉州懿心新材料科技有限公司 2025-03-11 CN claimed
US-6221397-B1 POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER BIOTECH AUSTRALIA PTY LIMITED (AU) 2001-04-24 US claimed
US-6197124-B1 CONTACTING COATED ARTICLE CONTAINING MULTIPLE COATING FILM HAVING LOWER COATING LAYER FORMED ON SUBSTRATE AND UPPER COATING LAYER FORMED ON THE LOWER COATING LAYER OR AN ADHERING SUBSTANCE WITH ACIDIC COMPOUND AND WATER TO DISSOLVE BINDER KANSAI PAINT CO., LTD. (JP) 2001-03-06 US claimed
EP-0646609-B1 Aqueous dispersion of an aqueous, hydrazine-terminated polyurethane TOYO INK MFG CO (JP) 2001-02-21 EP claimed
EP-1012208-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-06-28 EP claimed
WO-1999011703-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (US) 1999-03-11 WO claimed
EP-0697448-B1 Two-component composition for aqueous paint KANSAI PAINT CO LTD (JP) 1999-01-13 EP claimed
US-5821295-A COLLOIDAL DISPERSION OF A CARBONYL CONTAINING UNSATURATED MONOMER AND A DIHYDRAZIDE COMPOUND KANSAI PAINT CO., LTD. (JP) 1998-10-13 US claimed
EP-0697448-A1 Two-component composition for aqueous paint KANSAI PAINT CO., LTD. (JP) 1996-02-21 EP claimed
US-4609420-A CORONA, CARBOXYLIC ACID DIHYDRAZIDE BASF AKTIENGESELLSCHAFT (DE) 1986-09-02 US claimed
US-4529772-A Containing alkyl (meth)acrylate BASF AKTIENGESELLSCHAFT (DE) 1985-07-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109865-A1 WATER-BORNE COATING COMPOSITION GLRA1, EGLN1, ADH1C CYP1A2 1702/4885TSHR 1925/4885NFKB1 4431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.