Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 9/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149555 | 1.00 | MEN1 (0.36) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL23114939 | 0.94 | MEN1 (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21149554 | 0.94 | MEN1 (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112156 | 0.91 | MGLL (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112155 | 0.91 | MGLL (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL28407633 | 0.89 | MEN1 (0.33) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21149553 | 0.89 | MEN1 (0.33) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL28407635 | 0.89 | MEN1 (0.33) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL29640161 | 0.88 | EP300 (0.35) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112176 | 0.84 | MGLL (0.38) | MEN1KMT2AELANEMGLLROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-B | 1-Benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |