Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 3/20 | 0.31 |
| ▸ | MMP2 | P08253 | 3/20 | 0.31 |
| ▸ | MMP9 | P14780 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP14 | P50281 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21149553 | 1.00 | MEN1 (0.33) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL28407633 | 1.00 | MEN1 (0.33) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112221 | 0.92 | MGLL (0.35) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112222 | 0.92 | MGLL (0.35) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21112223 | 0.92 | MGLL (0.35) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL23114939 | 0.90 | MEN1 (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21149554 | 0.90 | MEN1 (0.37) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL29640161 | 0.89 | EP300 (0.35) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL21149555 | 0.89 | MEN1 (0.36) | MEN1KMT2AELANEMGLLROCK2 | |
| SCHEMBL28403733 | 0.89 | MEN1 (0.36) | MEN1KMT2AELANEMGLLROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212832-A | 1-benzyl-2-imino-4-phenyl-5-oxoimidazolidine derivatives as HIV protease inhibitors | 吉利德科学公司 | 2020-05-29 | — | — | CN | disclosed |