Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23963838 | 0.90 | ROCK2 (0.81) | ROCK2ROCK1 | |
| SCHEMBL21790245 | 0.87 | ROCK2 (0.79) | ROCK2ROCK1 | |
| SCHEMBL21790249 | 0.87 | ROCK2 (0.79) | ROCK2ROCK1 | |
| SCHEMBL21790286 | 0.85 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL21790292 | 0.85 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL19932282 | 0.85 | ROCK2 (0.76) | ROCK2ROCK1 | |
| SCHEMBL23633797 | 0.84 | ROCK2 (0.73) | ROCK2ROCK1 | |
| SCHEMBL23866454 | 0.83 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL23927641 | 0.83 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL2775983 | 0.83 | ROCK2 (1.00) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111217834-B | Nitroxide derivatives of ROCK kinase inhibitors | 维眸生物科技（上海）有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-111217834-B | Nitroxide derivatives of ROCK kinase inhibitors | 维眸生物科技（上海）有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-111217834-A | Nitroxide derivatives of ROCK kinase inhibitors | 维眸生物科技（上海）有限公司 | 2020-06-02 | — | — | CN | disclosed |