Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CPA3 | P15088 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087077 | 1.00 | FOLH1 (0.63) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL30684570 | 0.89 | FOLH1 (0.52) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL16128221 | 0.88 | ABCB1 (0.57) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL11306029 | 0.87 | FOLH1 (0.49) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL25183100 | 0.86 | CTSK (0.51) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL24447455 | 0.86 | CTSK (0.51) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL6420482 | 0.86 | FOLH1 (0.48) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL27519798 | 0.86 | ABCB1 (0.53) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL6705137 | 0.86 | ABCB1 (0.53) | FOLH1ABCB1ITGB3ITGA2BCTSL | |
| SCHEMBL25178768 | 0.85 | ABCB1 (0.50) | FOLH1ABCB1ITGB3ITGA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400521-B | Improved preparation method of 5R-benzyloxyaminopiperidine-2S-formate and oxalate thereof | 新发药业有限公司 | 2020-05-08 | — | — | CN | claimed |
| CN-109400521-B | Improved preparation method of 5R-benzyloxyaminopiperidine-2S-formate and oxalate thereof | 新发药业有限公司 | 2020-05-08 | — | — | CN | disclosed |